GC-MS analysis and Characterization of antimicrobial compounds from endangered tree species HumboldtiabourdilloniiPrain.from Southern Western Ghats.
The aim of the Present study was to investigate the antimicrobial potential of extracts from endangered medicinal plantHumboldtiabourdillonii, which are commonly used by the tribal’s of Western Ghats for the treatments of various diseases was evaluated against few pathogenic bacterial strains. The medicinal plants were extracted using solvents such as ethanol, methanol and acetone. The antibacterial test was performed against Pseudomonas aeruginosa, Staphylococcus aureus, Methicillin resistant staphylococcus aureus, Salmonella typhi, Vibrio cholerae,and Proteus mirabilis, and antifungal test performed againstRhizoctoniasolani, Trichodermaviride, Macrophominaphaseolina, a common storage fungus by using the agar diffusion assay. The medicinal plant exhibited antimicrobial activity against all the nine pathogenic microbial strains. Particularly, the methanol extract of medicinal plants having certain
active compounds showed better antibacterial and antifungal activity against the pathogenic microbial strains. Antimicrobial compounds were identified and
characterized using GC-MS Chromatography. These resultsclearly suggest that they can form the basis for the development of the novel broad spectrum of antibacterial formulation