Nickel (II) and Iron (II) Complexes with Azole Derivatives: Synthesis, Crystal Structures and Antifungal Activities

  • Karthigeyan.V Assistant Professor & Head, Sri Vidya Mandir Arts & Science College, Katteri, Uthangarai.

Abstract

Two new complexes of nickel (II) with 4-amino-3, 5-bis(pyridyl)-1, 2, 4-triazole (abpt) and iron (II) with 2-(3-phenyl-1H-pyrazole-5-yl) pyridine (phpzpy) have beenĀ  synthesized and characterized by elementalanalysis and IR spectroscopy. The crystal structures of the complexes have been determined by single crystal X-ray diffraction techniques. In the nickel and iron complexes, the ligands are coordinated through nitrogen atoms in bidentate manner. The ligands and their respective complexes have been tested for their antifungal activity against Aspergillus niger, Aspergillus flavus, and Candida albicans. From the study, the complexes showed enhanced activities against the tested organisms compared to the ligands.

Published
2016-05-30